Cute Honey: Bunny Girl combines strategic elements with tower defense and attractive anime girls. The player will have to use props in each scenario, which helps reduce the main character's stamina and stop the Ghost from falling into human civilization. The plot centers on a succubus named Eliza. She works in a bar and unexpectedly runs into a gentle singer. She wants to hide her romantic feelings because she is not allowed to be intimate with people.

The nature of the main character makes it difficult to control her own intentions, which can arouse suspicion from reporters. She needs to hide her identity from her lover, and she also wants the initial romantic relationship to develop into something happier and more rewarding. In the strategic adventure, gamers will need to use items from each scene to reduce the power of the succubus while achieving their goals.

The user observes the interesting life events of Eliza, who finds herself on the upper world in human form. As you progress, you gain access to a variety of CG scenes and images in the form of adult content. The gameplay features many hidden icons and surprise activities that are unlocked by exploring side items and completing optional objectives.