Despair: Blood Curse immerses gamers in a chilling third-person survival horror experience. In this title, the user takes on the role of Anna, a young woman coping with the mysterious death of her mother. The story unfolds when a lady receives a letter from her sister claiming that their mother has become a victim of something evil. Wanting answers, the person sets off on a dangerous journey to her childhood home. Upon her return, Anna is confronted with the eerie atmosphere of the looming mansion. The game's non-linear gameplay allows users to go through a series of puzzles while fighting against nightmarish enemies emerging from the depths of hell.

The storyline unfolds gradually, weaving itself into a narrative tapestry that reveals the family tragedy at the heart of the story. The mansion, shrouded in mystery, becomes a maze of suspense as Anna tries to piece together the mystery of her mother's untimely death. As users delve deeper into the shadows of Despair: Blood Curse, they are faced with inexorable forces seeking to thwart the lady's investigation. The atmosphere of the title is filled with tension, which is enhanced by the constant feeling of persecution by an invisible evil. The non-linearity of the gameplay forces users to be on alert, making it impossible to predict what horrors might unfold around every corner.