At the center of the plot Girlish Grimoire Littlewitch Romanesque: Editio Perfecta there is a powerful wizard named Domino. Unlike many of his colleagues, the protagonist believes that magic is not just a tool for achieving one’s own goals. It is much more complex and requires thorough study and, of course, respect. The others ridicule his assumptions and offer to prove they are right by making a bet. Domino believes in his own beliefs and agrees.

The essence of the dispute is that, using a revolutionary approach to magic, the protagonist is obliged to teach two girls magical skills in just three years. Usually the learning process takes more than ten years. Although the task itself is difficult, it is also made more difficult by the young students. These are young, cheerful and incredibly capricious girls who have more than just their studies on their minds. They are much closer to entertainment and communication with men, even adults like their newly-minted teacher.

Girlish Grimoire Littlewitch Romanesque: Editio Perfecta is based on dialogues, in which the main character has to train future witches and enter into various kinds of relationships with them. They can remain only professional, but if desired, the gamer can always go much further and start flirting. This is not difficult to do, given the fact that the girls themselves do not mind at all. With due effort, flirting can soon turn into romance and even intimacy with colorful scenes.