GTFO is a cooperative first-person shooter. Players gather in groups of 4 and explore the area. The location is underground labyrinths. They contain hidden treasures that need to be found and taken out. In addition to searching for valuable items, seekers will have to fight predatory cave dwellers. Many of them respond to sound. Therefore, you need to behave quietly to avoid trouble. The placement of enemies also changes upon replay.

Each round ends with an exit to the surface. According to the gameplay, you need to collect weapons, jewelry and other valuables. In addition, you need to carefully plan your return journey. Inventory is limited. For one fighter there are two guns, one melee weapon and a tool. Equipment may vary. This is a pistol, shotgun, rifles. There are also more specialized objects in the arsenal. Among them are glue guns for sticky traps, scanners for searching for enemies, and machine guns for defense. Firearms must be used with caution. The amount of ammunition is limited. In addition, there is a risk of injuring allies.

In addition to shootouts, GTFO offers teamwork. Various puzzles will arise along the heroes' path. They can only be solved by working harmoniously together. If anyone decides to go through the adventure alone, they will die.