Humorous shooter action High On Life are set on a futuristic version of Earth, the lore of which is directly based on the known television universe. The main character is an inglorious guy who has nothing to boast about. His only achievement is graduating from an educational institution. His life is a banal swim with the flow, where nothing pleases him. But then disaster strikes – an insidious extraterrestrial group with criminal tendencies began to set up its own illegal market and was already scouring the planet to reach those who wanted to spread nasty things. Having learned about this, the protagonist's sense of justice surged, and he sets off on an adventure. His new goal is to prevent the threat and become a successful intergalactic mercenary.

In High On Life, the central character will visit many authentic celestial bodies in order to catch the leader of the cartel Garmantuus and his subordinates, who are spreading the bandit’s influence to neighboring systems. In battles with enemies, he uses a fantastic weapon, which is a marvelous blaster with eyes in the back, looking at the owner. The adventurer is actively looking for employers and strictly fulfills the terms of the contract in order to receive the required remuneration and spend on the purchase of new equipment or weapons. All the action takes place in a colorful environment with bright colors, crazy drive and genuine emotions.