Jumper: Griffin's Story immerses gamers in an action-packed teleportation setting as seen in the film it is inspired by. Taking control of Griffin, a character who plays a key role in the storyline, users set out on a quest for revenge on the Paladins, a mysterious organization responsible for the death of his parents. Although he is not the central figure of the film, his story is set in the same universe, providing gamers with an alternative take on the funny story of jumpers and their relentless pursuers.

The action takes place in various locations featured in the film: the picturesque landscapes of Nepal, the bustling metropolis of Tokyo, the historical charm of Rome and the iconic cityscape of New York. This geographic diversity not only adds visual richness, but also contributes to strategic gameplay. Griffin's teleportation ability is a key gameplay mechanic, allowing gamers to stay ahead of enemies, strike unexpectedly from unusual angles, and discover hidden paths to enhance the title's experience.

As they progress through Jumper: Griffin's Story, gamers are faced with relentless persecution from the paladins, which adds an extra edge to the game. The developers originally integrated the rage counter into the dynamics of the gameplay. This meter is constantly replenished as Griffin collides with enemies or takes damage. Once charged, the user gets the opportunity to carry out a crushing attack, causing significant damage to all nearby enemies.