Live with Mary immerses the user in the role of Danny, who is tasked with managing his sister's household, where he encounters Mary. Within 7 days he will have to win Mary's interest in order to achieve the desired result. In this 3D third-person title, gamers control Danny's interactions and experiences in a home environment. The storyline unfolds through action-packed scenes and an English voice-over, providing an engaging narrative backdrop. Users perform various actions to establish a relationship with a lady, including talking, buying gifts, cooking and participating in various entertainment. These actions help strengthen the relationship between the couple and advance the storyline.

In addition, gamers can explore the intricacies of the house, discovering and collecting various items along the way. Cooking dinners for Mary and playing mini-games such as puzzles not only add variety to the gameplay, but also allow gamers to earn money to buy gifts and other items to further strengthen their bond with the girl. Additionally, Live with Mary features a gallery system where gamers can catalog and view photos and videos found during gameplay. This gives the game an additional level of immersion and encourages careful exploration and interaction with the game environment.