The Last Man tells the story of a special forces combat team that once went out on an urgent call. There was an accident at a scientific center and a test subject escaped from captivity. When the squad arrives at the building, they find it covered in human remains and blood. And almost immediately the entire group is destroyed by an alien monster that has managed to multiply and spawn dozens of no less hungry copies. Only one fighter survives in this hell, but he still has to get to the exit and destroy the alien threat in the bud. The main opponent in The Last Man are humanoid aliens. They are 3 meters tall, clawed and eyeless, and most of their heads are occupied by giant jaws. Hand-to-hand combat with such an opponent is almost guaranteed suicide.

Therefore, the main character has to rely on tactics, stealth and long-range weapons. There are 9 types of weapons with different advantages and disadvantages. For example, a sniper rifle will allow you to destroy a monster at a considerable distance and silently. In addition, there are 4 modes with different levels of difficulty. Passing on hardcore allows players to see all the locations, as well as gain access to other content. Depending on the decisions that the main character makes, the ending of the plot changes. The developers added 6 different endings.