Neon Blight transports the player to an alternate future. The action takes place in a metropolis filled with a cyberpunk atmosphere. The game character is a blue-haired girl – the owner of a weapons store. The game combines the adventures of the main character and the development of the store. The cyberpunk world is filled with ill-wishers and dangers and is open to exploration. The character is controlled on a 2D plane, with a view of the events from above. The gameplay is accompanied by electronic music, which allows you to fully experience the atmosphere of cyberpunk.

You can get new weapons by taking them from dead enemies. In search of prey, the heroine goes into danger and deals with criminals. The plot develops as the city is explored and the character develops. Opponents can be either ordinary bandits with machine guns or unique bosses. You can travel not only through the streets of the metropolis, you can find yourself in the underground underground and forest. Also in the city you can conduct dialogues with non-player characters and even make friends with them. For example, you can have a drink at a bar and chat with the bartender.

Neon Blight has a huge arsenal of weapons available for battle. There are both katanas or machine guns familiar to players, as well as unique blasters and so on. For each successful battle, the player earns money and experience points, which can be spent on improving the character's characteristics or expanding the store.